Kidney Disease in Rats

Chronic Progressive Nephrosis



  • Lethargy
  • Weight loss
  • Kidney and urinary problems
  • Protein in urine (proteinuria)
  • Fixed specific gravity of urine (isothenuria)


Glomerulonephrosis is hereditary in rats. Some other causes for the kidney disease include:

  • High caloric intake
  • Obesity
  • An excessively high-protein diet
  • Old age


The veterinarian will conduct blood and urine tests on the rat to confirm the diagnosis. A rat with glomerulonephrosis will normally have an excessive amount of protein in its urine. Its urine will also have a fixed specific gravity; this measures the kidney's ability to concentrate or dilute urine in relation to plasma.

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