Cats can be easily stressed or become anxious with changes in routine. Thanksgiving and the celebrations that often accompany the holiday are, for many cats, a big change in routine. Because stress can cause disease for your cat, you’ll need to take steps to minimize the stress for your cat.
Make sure your cat has a private area where he can retreat from the celebrations, if desired. For particularly skittish cats, restriction to an area of your home where celebrations are not taking place may be worth consideration. Your cat may be more comfortable and safer away the commotion.