Q. For 3 days I've noticed orange urine outside the litter box, lethargy in a 9-yr old cat. Is she in pain? Is this an emergency?

A. I would add that truly "orange" urine could be a sign of liver disease, as severe liver disease often results in an excess of the pigment bilirubin (which is yellow) in the blood. The excess consequentially ends up in the urine, and can cause it to appear orange. I do recommend that you don't wait until Monday but seek treatment today to determine what's going on with your cat.

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A. The orange coloring you speak of makes me suspicious of blood in her urine. Although crystalluria and bladder stones are more emergent in male cats, but can cause significant problems in female cats as well. Secondary to crystalluria would be a bacterial infection, either require medical care. Either of these conditions would be painful, and will not resolve in their own.

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