A. Complete loss of appetite is never something to be ignored and rarely something you can solve without the help of a Vet if it's been more than a couple days. I can see she is 8 years old and unspayed, is she drinking a lot? Is she lethargic? If so she could have developed a uterine infection which is an emergency. It could also be a simple gastro intestinal infection that could be resolved with some medications.
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