A. Frontline is a flea and tick medication and is given topically. Dewormers typically treat internal parasites and are given orally. Most dogs should be just fine being given both medications as they do very separate things and should not affect each other.
However, if your puppy appears to be reacting poorly to the medications, giving him a bath to wash off any remaining Frontline and contacting your vet is best. Your vet can recommend additional treatment to help your puppy feel better if needed. Signs of ill-health to look out for include vomiting, diarrhea, lethargic, looking confused or disoriented, or visibly shaking or twitching.
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