Arteriovenous Malformation of the Liver in Cats
Intrahepatic arteriovenous (AV) fistula is generally a congenital based condition, which causes abnormal passages to develop between the proper liver (hepatic) arteries and the inner liver (intrahepatic) portal veins. It can also develop through surgical injury, trauma, and abnormal tissue or bone growth (neoplasia). Although this condition is uncommon in cats, it does occur.
This severe illness can be addressed with fair results when a proper diagnosis has been settled on. Most treatment will be on an outpatient basis and will include a planned diet, dietary restrictions, and long term observation.
Symptoms and Types
Cats suffering from AV fistula may show lethargy, anorexia, vomiting, diarrhea, weight loss, excessive thirst (polydipsia), dementia, and abdominal swelling. There are several other signs of AV fistula, such as:
- Ascites (fluid in the abdomen)
- Congenital heart malformations
- Abnormal portal vein coagulation (thrombosis)
- Protein loss in the kidney (nephropathy)
- Intestinal abnormality (enteropathy) hypertension
- Liver disease, cirrhosis of liver
The central nervous system may also be affected by this condition. Symptoms can include:
- Distemper and other infectious disorders
- Lead poisoning, water on the brain (hydrocephalus)
- Idiopathic epilepsy
- Metabolic disorders
- Brain degeneration associated with liver failure (hepatic encephalopathy)
There is no particular breed that shows a higher predisposition than another. Hepatic AV is a vascular (vessel) malformation that is genetically determined during the embryonic stage of development - also referred to as embryologic anlage. Most conditions begin to show at an early age. In some cases of AV, surgical injury, trauma, or tumor growth (neoplasia) can lead to the problem.
The disorder can be tested for by conducting a complete blood count (CBC), biochemistry, and urinalysis techniques, as well as coagulation tests, abdominal (peritoneal) fluid analysis, and an evaluation of bile acids (digestive secretion from the liver). X-rays, ultrasounds, liver biopsies, and explaratory laparotomies (incision into the abdominal wall) are other exams that may help to diagnose the liver malformation.