A. That depends on the frequency and duration of the seizures. Of course it would be better, if someone is at home when a seizure happens, so that the dog can be taken to a vet if the seizure lasts 5 minutes or longer. But usually, unless seizures happen multiple times a day or the dog is not stable on seizure medication, there is very little you can do other than wait it out. So whether the dog can be home alone depends on the individual. Best ask your vet who knows your dog and can assess the situation.
A. It isn't ideal but unfortunately most pet owners have to work. If your pet is on anti-seizure medication(s) then it would be assumed that most of the major seizures are under control. If the seizures are not under control and you are worrying about seizures occurring during the hours that you are not home then an adjustment in his ant-seizure medications may be needed and you should discuss this with your vet. It is not unheard of to have a pet on multiple anti-seizure meds because they all work on different areas of the brain.
So to sum it up, if your pet is not having seizures on the days and hours that you are home and you are not seeing any evidence of break through seizures while you are gone (i.e. urine or feces on the floor, knocked over house ware, dazed pet with altered mentation when you come home), then it is safe to say that your pets seizures are probably being managed well. Another option is to have a camera surveillance set up in your house if you are still concerned.
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