A. Sometimes it resolves spontaneously, it goes away, but can recur in intervals.
A. At this time, the treatment of choice is doxycycline by mouth.. Doxycycline is an antibiotic, but it also has immunomodulating properties and it is believed it is these properties that are effective in treating plasma cell pododermatitis. About 50% of cats with pillow paw will show a good response after two months of therapy. When the condition is in remission, the doxycycline is continued for several months before discontinuing and seeing if the condition recurs. So it takes time to see a result.
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