A. Benadryl is often prescribed for anxious or aggressive cats prior to a vet visit to help calm them. The usual dose is 1 mg per pound (or 10 mg if you cat is 10 lbs). An interval of 2 hours prior to the visit should be fine. However, please understand that Benadryl will not knock your cat out - just make it calmer, more tractable for easier handling.
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